Recombinant Human TFF2 protein CD00833 from Bioassay Technology Laboratory

Description

Trefoil factor 2 encoded by the TFF2 gene in humans, belongs to the trefoil factor family that consists of three members named TFF1, TFF2 and TFF3. They are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. The TFFs are stable secretory proteins expressed highly in the gastrointestinal tract (gastric mucosa). TFF2 can inhibit gastrointestinal motility and gastric acid secretion. Additionally, it functions as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains

Product Specs
ItemRecombinant Human TFF2 protein
CompanyBioassay Technology Laboratory
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberCD00833
Quantity5 ug
Molecular WeightApproximately 12.0 kDa, a single non-glycosylated polypeptide chain containing 106 amino acids, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds
HostEscherichia coli
FormatLyophilized from a 0.2 µm filtered concentrated solution in 20 mM PB, pH 7.4, 130 mM NaCl
Research AreaOthers
Purity> 97 % by SDS-PAGE and HPLC analyses
ActivityFully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human MCF-7 cells is less than 10 ng/ml, corresponding to a specific activity of > 1.0 × 105 IU/mg
NCBI Full Gene Nametrefoil factor 2
NCBI Gene AliasesSML1, SP